We help the biggest and brightest
have confidence in their data, in-silico models and decisions.

Pharmaceutical & Academic

PREMIER Virtual Environmental Risk Laboratory

We are part of a multi-disciplinary team delivering a new EU-funded platform for the prioritization and risk evaluation of Active Pharmaceutical Ingredients in the environment. We are developing the digital assessment system at the heart of the PREMIER IMI2 project, working in partnership with AstraZeneca, GlaxoSmithKline, Bayer, Bristol-Myers Squibb, Novartis, Sanofi, Eli Lilly, Merck and many others.

Read more on the PREMIER website.

Pharmaceutical & Academic

3Rs Focused Virtual Disease Laboratories

Funded by the NC3Rs (focused on the 3Rs for the replacement, refinement & reduction of animal testing for scientific purposes), we have developed virtual disease laboratories to reduce/replace the need for pre-clinical animal models in therapeutic discovery/development for immune mediated inflammatory diseases like Sarcoidosis and Leishmaniasis and to de-risk clinical trial design for toxicology testing.

Read more on the NC3Rs website.

Pharmaceutical & Academic

Maximise for Data Sharing and Automating Toxicity Predictions

Funded by the NC3Rs, we partnered with Syngenta, Corteva and the University of York to develop the Maximise software platform, combining modelling with data sharing and reuse and automating toxicity prediction for new formulations. Maximise integrates data from multiple sources and employs machine learning to classify data & protect sensitive data that is shared.

Read more on the NC3Rs website.

Pharmaceutical R&D

Optimisation of Mathematical Models

We are working with one of the world’s largest biotech companies to re-implement a complex mathematical model for the trafficking of CAR T-cells, converting C and Python code into high-performance software. Our Simomics Evidence technology makes the code more accessible and reusable, exposing the provenance of data, evidence and assumptions.

Environmental Stewardship

DEFRA Decision and Intervention Support Tools

Department for Environment, Food & Rural Affairs (DEFRA) bespoke tools including an Evidencing tool to reduce the effort involved in querying documentation using graph searching algorithms and a decision support tool to visualise impacts of landscape management interventions based on a database of scientific literature.

Personal Care R&D

Reason for Goal Structuring Notation Safety Cases

A world-leading personal care company has been using our Reason software since 2016 to assist with their toxicology risk assessments. We continue to be engaged to explore integration opportunities with their environmental risk assessment work.

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